The ability to use fat as fuel combined with the distribution of fast and slow-twitch muscle fibres are important factors affecting endurance. The PPARA protein plays a role in these.

Global population distribution:

Source: 1000 Genome Project. Global averages for both sexes

Global population distribution:

Source: 1000 Genome Project. Global averages for both sexes

PPARA: CC

16%

PPARA: GC

23%

PPARA: GG

61%

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