One version of the ACE gene has been found in elite endurance athletes and every climber tested to date who has ascended over 8,000m. The other version is associated with improved power and strength performance.


Global population distribution:

Source: 1000 Genome Project. Global averages for both sexes

ACE: II

30%

ACE: ID

46%

ACE: DD

24%

More about ACE

The ACE gene encodes an enzyme called Angiotensin Converting Enzyme (ACE). This enzyme produces angiotensin II, a hormone that can constrict blood vessels and increase blood pressure. This, in turn, influences blood flow and metabolism in muscles. The short version of the ACE gene, the I allele, is associated with producing lower amounts of the ACE protein.

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