Variations in this gene will alter the expression of MCT1. This will determine how quickly lactic acid accumulates during exercise.


Global population distribution:

Source: 1000 Genome Project. Global averages for both sexes

MCT1: AA

13%

MCT1: TA

38%

MCT1: TT

49%

More about MCT1

Monocarboxylate transporters (MCT) are involved in the movement of metabolically important substances including lactate. MCT1 and MCT4 are the most important for lactic acid transport. MCT1 is found most abundantly within slow twitch fibers while MCT4 is found more in fast twitch fibers. These transporters allow the transfer of lactate from muscles into the blood and mitochondria.

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