Home How it works Genes we analyze

ACE

A gene for endurance

A particular version of the ACE gene has been found more often in elite endurance athletes, and every climber tested to date who......

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ACTN3

A gene for speed

ACTN3 is the world’s most famous ‘gene for speed’. This gene encodes for α-actinin-3, a protein that has been linked to greater......

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CYP1A2

A gene for caffeine metabolism

Caffeine has been used by athletes for a long time as a performance-enhancing drug. Studies have shown that taking caffeine......

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FTO

A gene for appetite

Genetics is known to influence food cravings, with carriers of a particular version of the FTO gene seemingly biologically wired......

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IL15RA

A gene for muscle volume

This gene is linked to the prevention of muscle breakdown as well as lean body mass and can affect how quickly individuals......

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LCT

A gene for lactose tolerance

Lactose tolerance is the ability to digest the lactose in milk and other everyday dairy products. For the majority of people,......

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MSTN

A gene for hypertrophy

Skeletal muscle growth in response to training is determined by genetics, and a rare version of the MSTN gene, which encodes the......

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PGC1A

A gene for aerobic capacity

As well as being a marker for good health, having a high aerobic capacity enables your body to work harder during prolonged......

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PPARA

A gene for fat burning

The ability to switch use fats as fuel over carbohydrates combined with the distribution of fast and slow-twitch muscle......

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UCP2

A gene for metabolism

Genetic variations in uncoupling proteins are thought to lead to differences in the efficiency of people's metabolism. We......

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HERC2

A gene for eye colour

Eye, hair and skin colour vary around the world because of the production of a pigment called melanin. One gene in particular,......

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ADRB2_1

A gene for adrenaline signalling

The fight-or-flight hormone, adrenaline, functions as a signalling molecule by binding to a protein coded for by the ADBR2 gene......

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ADRB2_2

A gene for adrenaline signalling

The fight-or-flight hormone, adrenaline, functions as a signalling molecule by binding to a protein coded for by the ADBR2 gene......

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AGT

A gene for blood pressure regulation

The protein angiotensinogen, which is produced by the AGT gene, is one of the initial components of a system which helps regulate......

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AKT1

A gene associated with aerobic exercise response

The AKT1 gene codes for an enzyme related to muscle building and metabolism. Some of us carry a particular version of this gene......

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AMPD1

A gene for energy production

AMPD is an enzyme that plays a role in anaerobic capacity and leads to fast accumulation of lactate after sprint exercises. We......

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APOA2

A gene for response to saturated fat intake

The APOA2 gene codes for a protein that is thought to play a role in fat metabolism, insulin sensitivity and......

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APOA5

A gene for blood triglyceride levels

The APOA5 gene codes for the APOA5 molecule. This molecule plays an important role in regulating blood triglyceride levels.......

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BDKRB2

A gene for vascular function

Widening of the blood vessels and therefore blood flow and blood pressure is regulated, amongst other things, by a molecule called......

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CKM

A gene related to muscle energy

Creatine kinase, encoded by the CKM gene, is an enzyme which influences the energy systems used in your cells.  Your......

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CLOCK

A gene affecting sleep cycle

The National Sleep Foundation has recommendations adults between the ages of 18-64 to sleep 7-9 hours per night. Sleep duration......

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CNTF

A gene for nerve activity

Ciliary neurotrophic factor (CNTF) is a protein which functions mainly in the nervous system. It is involved in neurotransmitter......

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ESR1

A gene for testosterone levels

The ESR1 gene is one of the genes used in combination to determine your testosterone levels. This gene controls the expression of......

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HIF1A

A gene for response to low oxygen

The body uses several proteins to deal with conditions of low oxygen, one of them is HIF1a (coded by the HIF1a gene).  HIF1a......

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IGF1

A gene for regular growth/development

The IGF1 gene influences circulating levels of the IGF1 hormone which is necessary for muscle growth and development. Variants......

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IGF1_2

A gene for normal growth/development

The IGF1 gene influences circulating levels of the IGF1 hormone which is necessary for muscle growth and development. We test for......

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IGFBP3

A gene for regulating normal growth / development

IGF1 (insulin-like growth factor 1), a hormone that promotes cell growth and cell division in both children and adults, is......

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IL6

A gene for inflammation and recovery

The cytokine interleukin 6 (IL6, coded by the IL6 gene) is a signalling molecule that is produced in the muscles during exercise.......

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IL6R

A gene for regulating IL6 activity

The IL6R gene codes for the receptor of the interleukin 6 protein (IL6R) which is found on the surface of cells, as well as......

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MCT1

A gene for fatigue

Variations in this gene will alter the expression of MCT1 which allows the clearance of lactic acid. This determines the onset of......

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NOS3

A gene for blood flow

Nitric oxide synthase 3 (coded by the NOS3 gene) is an enzyme that facilitates the production of nitric oxide (NO). NO is......

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PPARG

A gene associated with fat and carb processing

The PPARG protein is a receptor involved in fat storage and glucose metabolism.  Variants of the PPARG gene have been......

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SHBG1

A gene for testosterone levels

The SHBG1 gene is one of the genes used in combination to determine your testosterone levels. Sex-hormone binding gobulin (SHBG)......

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SHBG2

A gene for testosterone levels

The SHBG gene is one of the genes used in combination to determine your testosterone levels. Sex-hormone binding gobulin (SHBG)......

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UCP3

A gene for metabolism

Genetic variations in uncoupling proteins are thought to lead to differences in the efficiency of people's metabolism. We test for......

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VDR

A gene for vitamin D processing / activation

Vitamin D influences immunity, bone health and testosterone levels.  The vitamin D receptor (coded for by VDR) is important......

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VEGFA

A gene for blood vessel formation

We test for a variation of the VEGFA gene linked to levels of the VEGFA molecule in the blood. This molecule is involved in......

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MSTNRARE

A gene for unusual muscle size and strength

Skeletal muscle growth is influenced by genetics and myostatin is a protein that can inhibit it. A very rare variation of the gene......

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ACVR1B

A gene for muscle strength

The muscle growth limiting protein myostatin (as explained in the MSTN gene report) is affected by a protein encoded by the ACVR1B......

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MTHFR

A gene for folate metabolism

The MTHFR gene is one of the genes involved in the folate cycle. MTHFR is an enzyme that converts dietary folate or folic acid to......

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MTR

A gene for homocysteine conversion

MTR is an enzyme that is necessary for the conversion of homocysteine to methionine. Methionine production is important as it......

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MTRR

A gene for methionine production

Another genetic variant we test for in the methionine cycle is in the MTRR gene. MTRR is an enzyme that is necessary for the......

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MC4R

A gene associated with overeating

The MC4R variant is involved in the regulation of appetite. It influences the expression of the melanocortin-4 receptor which is......

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ALDH2

A gene for alcohol metabolism

The ALDH2 is a gene variant involved in the oxidative metabolism of alcohol within the mitochondria. The rare allele of this......

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VDR_Taq

A gene for response to vitamin D

This VDR gene codes for the Vitamin D3 receptor. Vitamin D influences immunity, bone health and testosterone levels; with the......

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NMB

A gene for disinhibited eating

The NMB variant impacts the levels of a peptide from the gastrointestinal tract, which inhibits food intake through the influence......

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MTHFR_SNP2

A gene associated with folate metabolism

The MTHFR gene is one of the genes involved in the folate cycle. MTHFR is an enzyme that converts dietary folate or folic acid to......

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LPL

A gene associated with HDL cholesterol levels

The LPL gene encodes for the enzyme called lipoprotein lipase, which is involved in the breakdown of triglycerides Lower levels......

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SLC30A8

A gene associated with fasting glucose levels

The SLC30A8 gene is involved in regulation of insulin due to it coding for the zinc transporter protein member 8 which is found in......

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