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Variations in the NOS3 gene may influence the beneficial effects induced by exercise, such as a lowering of blood triglycerides levels.
Source: 1000 Genome Project. Global averages for both sexes
The NOS3 enzyme, coded by the NOS3 gene, facilitates the production of nitric oxide (NO). NO is involved in the widening of blood vessels by relaxation of the smooth muscle cells within their walls, which increases blood flow.