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Variations of the NMB gene are associated with disinhibited eating – the tendency to overeat in response to external or internal cues (e.g. emotions).
Source: 1000 Genome Project. Global averages for both sexes
NMB impacts the levels of a peptide that influences eating behaviors to inhibit food intake. Some of its biological roles are within the serotonergic system, stimulation of the pancreatic appetite hormone peptide YY and regulating output from the pituitary gland.