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A very rare version of the MSTNRARE gene is associated with greatly increased muscle growth.
The MSTN gene codes for a protein called myostatin (Latin for muscle stop). Myostatin restricts muscle growth, ensuring muscle cells don't grow too large. A very rare variation of the gene coding for myostatin (MSTN) results in a complete knock out (loss of function) of the gene, and results in an unusually greater muscle mass and strength.