One of the alleles for this gene variant has been linked to elevated high-density lipoprotein (HDL) cholesterol levels which provide anti-inflammatory actions that can improve health.


Global population distribution:

Source: 1000 Genome Project. Global averages for both sexes

LPL: AA

80%

LPL: AG

19%

LPL: GG

1%

More about LPL

The LPL gene encodes for the LPL enzyme involved in the breakdown of triglycerides. Lower levels of this enzyme lead to accumulation of triglycerides and increased levels of very-low density lipoproteins (VLDLs), which can negatively impact health.

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