The IL6R gene codes for the receptor of the interleukin 6 protein (IL6R) which is found on the surface of cells, as well as circulating freely around the body.  Due to its mobility, IL6R can influence the activity and function of interleukin 6, a molecule involved in pro- and anti-inflammatory responses.  Variations of the IL6R gene have been associated with the metabolic syndrome.


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Global population distribution:

Source: 1000 Genome Project.  Global averages for both sexes

IL6R: CC

10%

IL6R: AC

38%

IL6R: AA

52%

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