The ESR1 gene is one of the genes used in combination to determine your testosterone levels. This gene controls the expression of an estrogen receptor important for sexual maturity, reproductive function as well as roles within tissues such as the bones. One of the alleles has been associated with lowering the levels of circulating testosterone.

Note: the research cited for this gene is in reference to male testosterone levels. Due to differences in levels of sex hormones between men and women, the findings from these studies are not applicable to women.


Global population distribution:

Source: 1000 Genome Project. Global averages for both sexes

ESR1: AA

32%

ESR1: GA

44%

ESR1: GG

24%

More about ESR1

The ESR1 gene controls the expression of an estrogen receptor important for sexual maturity, reproductive function and roles within body tissues.

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