Different variants of this gene lead to a lower or higher expression of this receptor and are associated with hypertension risk.


Global population distribution:

Source: 1000 Genome Project. Global averages for both sexes

BDKRB2: CC

39%

BDKRB2: TC

45%

BDKRB2: TT

16%

More about BDKRB2

Widening of the blood vessels and therefore blood flow and blood pressure is regulated, amongst other things, by a molecule called bradykinin. Bradykinin binds to a protein encoded by the BDKRB2 gene.

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