The ALDH2 is a gene variant involved in the oxidative metabolism of alcohol within the mitochondria. The rare allele of this variant is a form found more commonly in East Asian populations compared to the global population. It has been associated with the reddening of the face and neck following alcohol intake – a phenomenon known as ‘Asian Flush’.


Global population distribution:

Source: 1000 Genome Project. Global averages for both sexes

ALDH2: AA

1%

ALDH2: AG

5%

ALDH2: GG

94%

More about ALDH2

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