A gene associated with aerobic exercise response

The AKT1 gene codes for an enzyme related to muscle building and metabolism. Some of us carry a particular version of this gene that is linked to better resting metabolic factors and greater increases in VO2 max in response to aerobic exercise. Your FitnessGenes result tells you which version of this gene you carry.

The AKT1 gene contributes to the expression of the AKT1 enzyme (also known as PKB-α), which is an important molecule involved in the regulation of multiple processes including muscle growth and metabolism. It is believed to be a mediator of insulin function and enhances glucose uptake in muscle, fat cells and liver cells, amongst others. One particular version of this gene is believed to affect our baseline metabolic processes and response to exercise. Experiments have shown that increased expression of the AKT1 gene has an anabolic (growth) effect on muscle and bone, while reduced expression has a catabolic (breakdown) effect on fat.

You can find more information about the AKT1 gene in our member area at member.fitnessgenes.com where you can also find your results and what this means for you after your DNA has been analyzed by us. Head over to the shop to order your Fitnessgenes DNA analysis and genetic training system

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