AGT influences angiotensinogen levels which has associations with skeletal and cardiac muscle growth.


Global population distribution:

Source: 1000 Genome Project. Global averages for both sexes

AGT: CC

54%

AGT: CT

33%

AGT: TT

13%

More about AGT

The protein angiotensinogen is produced by the AGT gene. Angiotensinogen is converted in the body to angiotensin-II. Elevated plasma angiotensin-II levels act as a skeletal muscle growth factor; inducing hypertrophic signalling.

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