The MTHFR gene is one of the genes involved in the folate cycle. Variations of this gene influences how efficiently folate is processed.

Global population distribution:

Source: 1000 Genome Project. Global averages for both sexes

Global population distribution:

Source: 1000 Genome Project. Global averages for both sexes

MTHFR: AA

57%

MTHFR: AC

36%

MTHFR: CC

7%

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