The cytokine interleukin 6 (IL6, coded by the IL6 gene) is a signalling molecule that is produced in the muscles during exercise. It is thought to be involved in pro- and anti-inflammatory responses and to help nutrient mobilisation and delivery, making it important for performance and recovery. Variations in the IL6 gene can affect levels of IL6.  One variation has been associated with power athletes and better body composition.


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Global population distribution:

Source: 1000 Genome Project.  Global averages for both sexes

IL6: CC

5%

IL6: GC

19%

IL6: GG

76%

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