The muscle growth limiting protein myostatin (as explained in the MSTN gene report) is affected by a protein encoded by the ACVR1B gene.  One variation of ACVR1B has been associated with increased strength.


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Global population distribution:

Source: 1000 Genome Project. Global averages for both sexes

ACVR1B: GG

15%

ACVR1B: GA

43%

ACVR1B: AA

42%

More about ACVR1B

THE ACVR1B GENE

The ACVR1B gene encodes for the activin receptor type-1B and it is thought to play a role in myostatin signalling in muscle. The variation we look at is still relatively unexplored and we are waiting for further studies to fully understand how it affects strength.

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