New Gene Release: IL6

Thursday, March 31, 2016. Author Alex Auld

The Role of IL6

Cytokine Interleukin 6, more commonly referred to as IL6, is a signalling molecule that helps nutrient mobilisation and delivery during exercise. This makes it a key factor in both performance, and post exercise recovery.

Increased expression of IL6 has also been linked to lower levels of muscle damage following powerful contractions. This protective role of IL6, combined with improved muscle recovery, makes high expression of IL6 beneficial for power-based athletes.

However, higher IL6 expression can also result in adverse health effects, such as cardiovascular disease, due to an increased risk of inflammation in other tissues.

IL6 and Genetics

The expression of the IL6 molecule varies between the genotypes of the IL6 gene. Carriers of the GG variation produce the highest levels of IL6, making this genotype the most desirable for power based athletes. CG carriers therefore are seen to produce intermediate levels of IL6, whilst the CC genotype produces the lowest levels.

In addition to the benefits listed above, studies have shown that the G allele is associated with better body composition and greater improvements in VO2 max than the C allele, as found when results were compared following an 8-week training plan.

Your IL6 Result

So does your IL6 gene result give you a power advantage, or does it mean you should be reconsidering your recovery time after resistance based training? To find out, head over to the members area of – your IL6 report is now live!

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