A saliva sample, like a cheek swab, contains skin cells from the inside of your mouth (from which we extract DNA). We have found saliva samples to be more reliable than cheek swabs, especially when using the buffer solution to preserve the DNA sample. Despite what you may have seen in TV programmes, hair is not an especially reliable way of getting a DNA sample. Only the hair follicle, which is painful to remove, actually contains DNA. The shaft of the hair contains no genomic DNA.
We use the Genetic Laboratory based at the Erasmus Medical Center, Rotterdam, Netherlands.
The laboratory is highly-accredited and holds: certification to ISO 9001 for business processes, accreditation to ISO 17025 for laboratory testing and calibration services, compliance with Good Laboratory Practice (GLP), Good Clinical Practice (GCP) and current Good Manufacturing Practice (cGMP) for pharmaceutical studies and accreditation to ISO 17043 for the operation and management of proficiency testing schemes.
For more information about our laboratory, please visit: glimdna.org
Many dietary and training regimes fail because they are not tailored to an individual’s unique genetic make-up and lifestyle. By contrast, FitnessGenes analyze your DNA and lifestyle factors to provide personalized, actionable recommendations. Our diet and workout recommendations are based on gene variants that have been scientifically demonstrated to have an effect on health and fitness outcomes. For example, if your goal is to lose weight, our DNA analysis can inform you whether you have a genetic tendency towards overeating (e.g. you may carry risk alleles (variants) of certain genes like the FTO gene). Based on this information, we can create nutrition plans that recommend changes in meal frequency and macronutrient (protein, carbohydrate and fat) ratio, so as to minimise your risk of overeating and weight gain.
We have helped thousands of customers get fit, lose fat, get lean and gain muscle. One study of 530 FitnessGenes customers demonstrated that 97% found an analogous or improved effect compared to previous fitness plans.
In terms of individual customer feedback, one customer has written the following article on Buzzfeed.
No - we are not a diagnostic service or healthcare provider and therefore do not provide health reports or medical advice.
Our products are designed to help people meet fitness goals and are intended for informational and educational use only. They are not substitutes for medical advice, diagnosis and treatment from qualified health practitioners.
It is strongly recommended that you consult a physician or other qualified healthcare provider before making any changes to your lifestyle, diet or exercise routines.
DNA analysis can only test for food intolerances and sensitivities that have a strong genetic underpinning. In this regard, we tell you whether you’re likely to be lactose intolerant based on your LCT gene. We also inform you of how fast you are likely to metabolize caffeine based on your CYP1A2 gene.
We do not provide information on intolerances/sensitivities to other foodstuffs, including: gluten, wheat, yeast or histamine. This is because there is no clear, single gene variant associated with these intolerances.
Note that we also do not test for food allergies. Allergies are different from intolerances in that they involve a specific immune reaction. Food allergies must be diagnosed by a qualified healthcare practitioner, a process that may involve blood tests, skin-prick testing and other investigations.
No - the only food intolerance we test for at present is lactose intolerance. We don't test for gluten intolerance as there is not yet a clear, single, genetic variation linked to gluten intolerance (there is one linked to coeliac disease - but this is a medical / autoimmune condition, and is not an allergy or an intolerance to gluten).
We will soon be moving to a new DNA analysis technology that will allow us to test for a number of genetic variations which may be linked to gluten intolerance. If you are concerned about gluten intolerance or coeliac disease, it is recommended that you see your doctor. A blood test can help clarify whether it is gluten that you should be avoiding.
Collecting your DNA sample is safe, simple and non-invasive – it merely involves collecting about a tablespoonful of saliva in a tube. As long as you are sufficiently healthy to provide a saliva sample, you will be able to do the test.
Your DNA sequence is fixed throughout life, so your DNA results will not be affected by pregnancy or illness.
No - we only analyze gene variants related to diet, workout and fitness outcomes.
While some of these gene variants may happen to overlap with ancestry-related genes, we are unable to inform you of your ancestry or ethnic background from your FitnessGenes DNA results.
If you have already had your ancestry analyzed by 23andMe or AncestryDNA, we will soon be able to use your raw DNA data to generate your FitnessGenes DNA results and tailored workout and nutrition plans. We expect to have this facility ready by August 2018.